Berger KD, MacLean DM. “Mechanism of acid-sensing ion channel modulation by Hi1a.” J Gen Physiol.

Purohit R, Couch T, Rook ML, MacLean DM. “Proline substitutions in the ASIC1 β11-12 linker slow desensitization.” Biophys J.

Rook ML, McCullock TW, Couch T, Lueck JD, MacLean DM. “Photomodulation of the ASIC1a acidic pocket destabilizes the open state.” Protein Sci.

MacLean DM, Soto E. “Editorial: ASICs: Structure, Function, and Pharmacology.” Front Physiol.

Foley K, Altimimi H, Hou H, Zhang Y, McKee C, Papasergi-Scott MM, Yang H, Mayer A, Ward N, MacLean DM, Nairn AC, Stellwagen D, Xia H. “Protein phosphatase-1 inhibitor-2 protomotes PP1γ positive regulation of synaptic transmission.” Front Synaptic Neurosci.

Rook M, Miaro M, Couch T, Kneisley D, Musgaard M, MacLean DM. “Mutation of a conserved glutamine residue does not abolish desensitization of acid-sensing ion channel 1.” J Gen Physiol.

Rook M, Ananchenko A, Musgaard M, MacLean DM. “Molecular Investigation of Chicken Acid-Sensing Ion Channel 1 β11-12 Linker Isomerization and Channel Kinetics.” Front Cell Neurosci.

Couch T, Berger K, Kneisley D, McCullock T, Kammermeier P, MacLean DM. “Topography and motion of acid-sensing ion channel intracellular domains.” Elife.

Rook M, Musgaard M, MacLean DM. “Coupling structure with function in acid-sensing ion channels: Challenges in pursuit of proton sensors”. J Physiol.

Rook M, Williams A, Lueck JD, Musgaard M, MacLean DM. “Beta11-12 linker isomerization governs Acid-sensing ion channel desensitization and recovery”. eLife.

McCullock TW, MacLean DM, Kammermeier P. “Comparing the performance of mScarlet-I, mRuby3, and mCherry as FRET acceptors for mNeonGreen”. PLOS One.

Durham RJ, Paudyal N, Carillo E, Bhatia N, MacLean DM, Berka V, Dolino DM, Gorfe A, Jayaraman V. “Conformational spread and dynamics in allostery of NMDA receptors”. PNAS.

Carillo E, Shaikh S, BerkaV, Durham RJ, Litwin DB, Lee G, MacLean DM, Nowak LM, Jayaraman V. “Mechanism of modulation of AMPA receptors by TARP-gamma 8”. Journal of General Physiology.

MacLean DM, Durham RJ, Jayaraman V. “Mapping the conformational landscape of glutamate receptors using single molecule FRET.” Trends in Neurosci.

Chen J, Li L, Chen SR, Chen H, Xie JD, Sirrieh RE, MacLean DM, Zhang Y, Zhou MH, Jayaraman V, Pan HL. “The a2d-1-NMDA Receptor Complex is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions.” Cell Reports

Dolino DM, Chatterjee S, MacLean DM, Flatebo C, Bishop LDC, Shaikh SA, Landes CF and Jayaraman V. “The structure-energy landscape of NMDA receptor gating.” Nat. Chem. Biology

Coombs ID*, MacLean DM*, Jayaraman V, Farrant M and Cull-Candy SG. “Dual Effects of TARP γ-2 on Glutamate Efficacy Can Account for AMPA Receptor Autoinactivation.” Cell Reports

MacLean DM, Jayaraman V. “Deactivation kinetics of Acid Sensing Ion Channel 1a are strongly pH-sensitive.” PNAS

Vitrac H, MacLean DM, Karlstaedt A, Taegtmeyer H, Jayaraman V, Bogdanov M, Dowhan W. “Dynamic lipid-dependent modulation of protein topology by post-translational phosphorylation.” JBC

Shaikh SA, Dolino DM, Lee G, Chatterjee S, MacLean DM, Flatebo C, Landes C, Jayaraman, V. “Stargazin modulation of AMPA receptors.” Cell Reports

MacLean DM, Jayaraman V. “Acid Sensing Ion Channels are tuned to follow high frequency stimuli.” J Physiol.

Vitrac H, MacLean DM, Bogdanov M, Jayaraman V, Dowhan W. “Dynamic membrane protein topological switching upon changes in lipid environment.” PNAS

Sirrieh RE, MacLean DM, Jayaraman V. “A conserved structural mechanism of NMDA receptor inhibition: A comparison of ifenprodil and zinc.” JGP

Sirrieh RE, MacLean DM, Jayaraman V. “Subtype-dependent N-methyl-D-aspartate receptor amino-terminal domain conformations and modulation by spermine.” JBC

MacLean DM. “Constructing a rapid solution exchange system.” Ionotropic Glutamate Receptor Technologies.

MacLean DM, Ramaswamy S, Du M, Howe J, Jayaraman V. “Stargazin promotes closure of the AMPA receptor ligand-binding domain.” JGP

Lee G*, MacLean DM*,Ulrich H, Zhao C, Aronowski J, Jayaraman V. “RNA based antagonism of NMDA receptors.” ACS Chem Neurosci.

Ramaswamy S, MacLean DM, Gorfe AA, Jayaraman V. “Proton-mediated conformational changes in an acid-sensing ion channel.” JBC

MacLean DM. “TARPs modulate AMPA receptor conformations before the gating transitions.” J Physiol.

Sirrieh RE,MacLean DM, Jayaraman V. “Amino-terminal domain tetramer organization and structural effects of zinc binding in the NMDA receptor.” JBC

Ramaswamy S, Cooper D, Poddar N, MacLean DM, Rambhadran A, Taylor JN, Uhm H, Landes CF, Jayaraman V. “Role of conformational dynamics in alpha-amino-3-hydroxy-5-methylisoxazole-4-propinoic acid (AMPA) receptor partial agonism.” JBC

MacLean DM, Bowie D. “TARP modulation of AMPA receptor pharmacology: A problem of interpretation.” J Physiol.

MacLean DM, Wong AY, Fay AM, Bowie D. “Cations but not anions regulate the responsiveness to Kainate receptor agonists.” J NRS

MacLean DM. “The delta2 glutamate-like receptor undergoes similar conformational changes as other ionotropic glutamate receptors.” J NRS (image from Hansen et al., 2009)

Wong AY, MacLean DM, Bowie D. “Na+/Cl-dipole couples agonist binding to Kainate receptor activation.” J NRS

Kuang D, Yao Y, MacLean DM, Wang M, Hampson DR, Chang BS. “Ancestral reconstruction of the ligand binding pocket of family C G-protein coupled receptors.” PNAS